Engineering Biology Lab

Biodesign based on engineering principles

At the NUS Engineering Biology Lab, we apply engineering principles to design and build microbes with useful capabilities for medical and industrial applications, developing foundational platform tools to accelerate the design and engineering of the microbes.

Research areas

Optogenetics

We aim to control bacterial behavior with high spatial and temporal resolution using electromagnetic signals.

Biosensors

We aim to develop biosensors that, incorporated into our engineered cells, allow them to react to different external stimuli.

Modeling and software tools

We aim to develop computational tools to reproduce cell behavior to make engineering-based biodesign a reality.

Cell factories

We aim to engineer synthetic gene circuits that enable regulation of recombinant protein production using microbial cell factories.

Biofilm engineering

We aim to control biofilm development in order to obtain scalable, cost-effective bioproduction systems.

Therapeutic cells

We aim to use engineered bacteria to fight potentially deadly infectious diseases such as cholera.

News

02

April

Publication

Blue Light-Directed Cell Migration, Aggregation, and Patterning

By Zhang Jingyun, Luo Yuhuan and Poh Chueh Loo

03

Dec

People

Congratulations to Jingyun!

Jingyun defended his thesis. Congratulations!

22

Nov

Publication

Genetic Circuit Design Principles (Handbook of Cell Biosensors)

By Jing Wui Yeoh, Salvador Gomez-Carretero, Wai Kit David Chee, Ai Ying Teh and Chueh Loo Poh.

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