Eco-friendly biomanufacturing of flavonoid dyes in Escherichia coli via computer-mediated optogenetic regulation. The NUSGEM iGEM 2018 team developed a computer-mediated optogenetic regulation system as a technological platform for future biomanufacturing. The expression of enzymes involved in the biosynthetic pathway can be rapidly regulated by light. Burden-based cellular stress is monitored and regulated using custom hardware. More information can be found at their iGEM page.